PLG protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation; in ovulation it weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. It cleaves fibrin, fibronectin, thrombospondin, laminin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4 (810 aa)
(Homo sapiens)
Predicted Functional Partners:
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), m [...] (491 aa)
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; [...] (402 aa)
fibronectin 1; Fibronectins bind cell surfaces and various compounds including collagen, fibrin [...] (2477 aa)
plasminogen activator, urokinase receptor; Acts as a receptor for urokinase plasminogen activat [...] (335 aa)
secreted protein, acidic, cysteine-rich (osteonectin); Appears to regulate cell growth through [...] (303 aa)
histidine-rich glycoprotein; The physiological function is not yet known. It binds heme, dyes a [...] (525 aa)
kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an impor [...] (644 aa)
serpin peptidase inhibitor, clade C (antithrombin), member 1; Most important serine protease in [...] (464 aa)
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Activation of the C1 complex is u [...] (500 aa)
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Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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