GP6 protein (Homo sapiens) - STRING interaction network

GP6 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	GP6	glycoprotein VI (platelet); Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma- chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2 (620 aa)
		(Homo sapiens)
Predicted Functional Partners:
	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; Down regulates expression of stem cel [...] (512 aa)	•	•	•	0.998
	FYN	FYN oncogene related to SRC, FGR, YES; Implicated in the control of cell growth. Plays a role i [...] (537 aa)	•	•	•	0.994
	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Associates with a variety [...] (86 aa)	•	•	•	0.993
	COL1A1	collagen, type I, alpha 1; Type I collagen is a member of group I collagen (fibrillar forming c [...] (1464 aa)		•	•	0.992
	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Integrin alpha-2/beta-1 is a rece [...] (1181 aa)			•	0.992
	COL1A2	collagen, type I, alpha 2; Type I collagen is a member of group I collagen (fibrillar forming c [...] (1366 aa)		•	•	0.986
	CRP	C-reactive protein, pentraxin-related; Displays several functions associated with host defense- [...] (224 aa)	•		•	0.980
	SYK	spleen tyrosine kinase; Positive effector of BCR-stimulated responses. Couples the B-cell antig [...] (635 aa)		•	•	0.977
	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide; 3-phosphorylates the cellular phosphoi [...] (1102 aa)		•	•	0.963
	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)			•	0.963

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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