DDIT4 protein (Homo sapiens) - STRING interaction network

DDIT4 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	DDIT4	DNA-damage-inducible transcript 4; Inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death (232 aa)
		(Homo sapiens)
Predicted Functional Partners:
	TP53	tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)		•	•	0.984
	TSC2	tuberous sclerosis 2; In complex with TSC1, inhibits the nutrient-mediated or growth factor-sti [...] (1807 aa)		•	•	0.976
	TSC1	tuberous sclerosis 1; In complex with TSC2, inhibits the nutrient-mediated or growth factor-sti [...] (1164 aa)		•	•	0.975
	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Adapt [...] (245 aa)	•	•		0.959
	ATF4	activating transcription factor 4 (tax-responsive enhancer element B67); Transcriptional activa [...] (351 aa)			•	0.943
	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Adap [...] (247 aa)		•		0.899
	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; Adapt [...] (246 aa)		•		0.899
	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Ad [...] (255 aa)		•		0.899
	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; Adapte [...] (246 aa)		•		0.899
	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; Adap [...] (245 aa)		•		0.899

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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