version_number_image
  PDHB protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PDHB
pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (359 aa)
(Homo sapiens)
Predicted Functional Partners:
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the ov [...] (390 aa)
 0.999
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2; The pyruvate dehydrogenase complex catalyzes the ov [...] (388 aa)
 0.999
PDHX
pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogen [...] (501 aa)
 0.999
DLAT
dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall [...] (647 aa)
 0.999
DLD
dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage [...] (509 aa)
   0.999
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide; The branched-chain alpha-keto deh [...] (445 aa)
  0.982
DBT
dihydrolipoamide branched chain transacylase E2; The branched-chain alpha-keto dehydrogenase co [...] (482 aa)
    0.980
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1; Catalyzes the dephosphorylation and conc [...] (537 aa)
       0.959
LDHD
lactate dehydrogenase D (507 aa)
      0.905
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic (572 aa)
      0.905
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (1%)
Permalink