PDHB protein (Homo sapiens) - STRING interaction network

PDHB protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PDHB	pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (359 aa)
		(Homo sapiens)
Predicted Functional Partners:
	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the ov [...] (390 aa)	•	•	•	•	•	•	•	0.999
	PDHA2	pyruvate dehydrogenase (lipoamide) alpha 2; The pyruvate dehydrogenase complex catalyzes the ov [...] (388 aa)	•	•	•	•	•	•	•	0.999
	PDHX	pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogen [...] (501 aa)	•	•	•	•	•	•	•	0.999
	DLAT	dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall [...] (647 aa)	•	•	•	•	•	•	•	0.999
	DLD	dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage [...] (509 aa)	•			•	•	•	•	0.999
	BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide; The branched-chain alpha-keto deh [...] (445 aa)	•	•	•	•	•		•	0.982
	DBT	dihydrolipoamide branched chain transacylase E2; The branched-chain alpha-keto dehydrogenase co [...] (482 aa)	•			•		•	•	0.980
	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1; Catalyzes the dephosphorylation and conc [...] (537 aa)							•	0.959
	LDHD	lactate dehydrogenase D (507 aa)	•					•		0.905
	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic (572 aa)				•		•		0.905

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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