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  IL13 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL13
interleukin 13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (146 aa)
(Homo sapiens)
Predicted Functional Partners:
IL4R
interleukin 4 receptor; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1 [...] (825 aa)
     0.999
IL13RA1
interleukin 13 receptor, alpha 1; Binds IL13 with a low affinity. Together with IL4R-alpha can [...] (427 aa)
     0.999
IL13RA2
interleukin 13 receptor, alpha 2; Binds as a monomer with high affinity to interleukin 13 (IL13 [...] (380 aa)
      0.999
IL4
interleukin 4; Participates in at least several B-cell activation processes as well as of other [...] (153 aa)
      0.996
IL5
interleukin 5 (colony-stimulating factor, eosinophil); Factor that induces terminal differentia [...] (134 aa)
      0.994
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.993
IL2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
      0.992
IL8
interleukin 8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, [...] (99 aa)
       0.992
CCL11
chemokine (C-C motif) ligand 11; In response to the presence of allergens, this protein directl [...] (97 aa)
       0.992
IL9
interleukin 9; Supports IL-2 independent and IL-4 independent growth of helper T-cells (144 aa)
      0.987
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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