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  UGT1A1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate (533 aa)
(Homo sapiens)
Predicted Functional Partners:
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thi [...] (503 aa)
      0.977
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (543 aa)
      0.977
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (512 aa)
      0.977
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochromes P450 are a group of heme-thi [...] (516 aa)
      0.976
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6; Cytochromes P450 are a group of heme-thi [...] (491 aa)
      0.976
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9; Cytochromes P450 are a group of heme-thi [...] (490 aa)
      0.976
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8; Cytochromes P450 are a group of heme-thi [...] (490 aa)
      0.975
CES2
carboxylesterase 2 (intestine, liver); Involved in the detoxification of xenobiotics and in the [...] (623 aa)
      0.973
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19; Cytochromes P450 are a group of heme-th [...] (490 aa)
      0.972
SLC35A2
solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars f [...] (396 aa)
       0.972
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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