UGT1A1 protein (Homo sapiens) - STRING interaction network

UGT1A1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX- alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate (533 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thi [...] (503 aa)	•	•	0.977
	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (543 aa)	•	•	0.977
	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1; Cytochromes P450 are a group of heme-thi [...] (512 aa)	•	•	0.977
	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochromes P450 are a group of heme-thi [...] (516 aa)	•	•	0.976
	CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6; Cytochromes P450 are a group of heme-thi [...] (491 aa)	•	•	0.976
	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9; Cytochromes P450 are a group of heme-thi [...] (490 aa)	•	•	0.976
	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8; Cytochromes P450 are a group of heme-thi [...] (490 aa)	•	•	0.975
	CES2	carboxylesterase 2 (intestine, liver); Involved in the detoxification of xenobiotics and in the [...] (623 aa)	•	•	0.973
	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19; Cytochromes P450 are a group of heme-th [...] (490 aa)	•	•	0.972
	SLC35A2	solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars f [...] (396 aa)		•	0.972

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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