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  FOXA3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FOXA3
forkhead box A3; Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes (350 aa)
(Homo sapiens)
Predicted Functional Partners:
TTR
transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstr [...] (147 aa)
      0.965
AFP
alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well th [...] (609 aa)
      0.950
ALB
albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2 [...] (609 aa)
      0.940
TAT
tyrosine aminotransferase (454 aa)
      0.922
TFRC
transferrin receptor (p90, CD71); Cellular uptake of iron occurs via receptor-mediated endocyto [...] (760 aa)
       0.899
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble); Catalyzes the conversion of oxaloacetate (OAA) t [...] (622 aa)
      0.899
G6PC
glucose-6-phosphatase, catalytic subunit; Hydrolyzes glucose-6-phosphate to glucose in the endo [...] (357 aa)
      0.899
C4BPB
complement component 4 binding protein, beta; Controls the classical pathway of complement acti [...] (252 aa)
       0.899
ONECUT1
one cut homeobox 1; Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' [...] (465 aa)
       0.822
GCG
glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity [...] (180 aa)
       0.782
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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