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  IGF1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IGF1
insulin-like growth factor 1 (somatomedin C); The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity (195 aa)
(Homo sapiens)
Predicted Functional Partners:
IGFBP3
insulin-like growth factor binding protein 3; IGF-binding proteins prolong the half-life of the [...] (297 aa)
     0.999
IGFBP4
insulin-like growth factor binding protein 4; IGF-binding proteins prolong the half-life of the [...] (258 aa)
     0.999
IGFBP5
insulin-like growth factor binding protein 5; IGF-binding proteins prolong the half-life of the [...] (272 aa)
     0.999
IGFBP1
insulin-like growth factor binding protein 1; IGF-binding proteins prolong the half-life of the [...] (259 aa)
     0.999
IGF1R
insulin-like growth factor 1 receptor; This receptor binds insulin-like growth factor 1 (IGF1) [...] (1367 aa)
     0.999
IGFBP2
insulin-like growth factor binding protein 2, 36kDa; IGF-binding proteins prolong the half-life [...] (325 aa)
     0.999
INSR
insulin receptor; This receptor binds insulin and has a tyrosine-protein kinase activity. Isofo [...] (1382 aa)
     0.999
IRS1
insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. [...] (1242 aa)
      0.999
GRB10
growth factor receptor-bound protein 10; Plays a functional role in insulin and IGF-I signaling [...] (594 aa)
      0.998
IRS2
insulin receptor substrate 2; May mediate the control of various cellular processes by insulin (1338 aa)
      0.997
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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