PRL protein (Homo sapiens) - STRING interaction network

PRL protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	PRL	prolactin; Prolactin acts primarily on the mammary gland by promoting lactation (227 aa)
		(Homo sapiens)
Predicted Functional Partners:
	PRLR	prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin (PRL). Isof [...] (622 aa)	•	•	•	0.999
	POU1F1	POU class 1 homeobox 1; Transcription factor involved in the specification of the lactotrope, s [...] (317 aa)		•	•	0.999
	JAK2	Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)		•	•	0.996
	POMC	proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)			•	0.993
	IGF1	insulin-like growth factor 1 (somatomedin C); The insulin-like growth factors, isolated from pl [...] (195 aa)			•	0.992
	TSHB	thyroid stimulating hormone, beta; Indispensable for the control of thyroid structure and metab [...] (138 aa)			•	0.992
	TRH	thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anter [...] (242 aa)			•	0.991
	GHRH	growth hormone releasing hormone; GRF is released by the hypothalamus and acts on the adenohypo [...] (108 aa)			•	0.991
	FSHB	follicle stimulating hormone, beta polypeptide; Stimulates development of follicle and spermato [...] (129 aa)			•	0.990
	STAT5A	signal transducer and activator of transcription 5A; Carries out a dual function- signal transd [...] (794 aa)			•	0.989

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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