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  EN2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
EN2
engrailed homeobox 2 (333 aa)
(Homo sapiens)
Predicted Functional Partners:
FGF8
fibroblast growth factor 8 (androgen-induced); Stimulates growth of the cells in an autocrine m [...] (244 aa)
       0.967
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); Transcriptional corepressor t [...] (773 aa)
       0.921
WNT1
wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family [...] (370 aa)
       0.841
PAX2
paired box 2; Probable transcription factor that may have a role in kidney cell differentiation [...] (396 aa)
       0.826
LMBR1
limb region 1 homolog (mouse); Putative membrane receptor (490 aa)
       0.823
EGR2
early growth response 2; Sequence-specific DNA-binding transcription factor. Binds to two speci [...] (476 aa)
       0.823
SNCA
synuclein, alpha (non A4 component of amyloid precursor); May be involved in the regulation of [...] (140 aa)
       0.819
SHH
sonic hedgehog homolog (Drosophila); Binds to the patched (PTC) receptor, which functions in as [...] (462 aa)
       0.803
NT5E
5'-nucleotidase, ecto (CD73); Hydrolyzes extracellular nucleotides into membrane permeable nucl [...] (574 aa)
       0.776
PAX5
paired box 5; May play an important role in B-cell differentiation as well as neural developmen [...] (391 aa)
       0.772
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

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