CXCL3 protein (Homo sapiens) - STRING interaction network

CXCL3 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CXCL3	chemokine (C-X-C motif) ligand 3; Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes (107 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CXCL2	chemokine (C-X-C motif) ligand 2; Produced by activated monocytes and neutrophils and expressed [...] (107 aa)	•		•	•	•	0.989
	CCL19	chemokine (C-C motif) ligand 19; May play a role not only in inflammatory and immunological res [...] (98 aa)			•	•		0.988
	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); Has chemotactic [...] (107 aa)	•		•	•	•	0.986
	CXCR2	chemokine (C-X-C motif) receptor 2; Receptor for interleukin-8 which is a powerful neutrophil c [...] (360 aa)		•	•	•		0.985
	CCL20	chemokine (C-C motif) ligand 20; Chemotactic factor that attracts lymphocytes and, slightly, ne [...] (96 aa)	•		•	•		0.984
	CXCR1	chemokine (C-X-C motif) receptor 1; Receptor to interleukin-8, which is a powerful neutrophils [...] (350 aa)		•	•	•		0.983
	CCL5	chemokine (C-C motif) ligand 5; Chemoattractant for blood monocytes, memory T-helper cells and [...] (91 aa)			•	•		0.972
	CXCL16	chemokine (C-X-C motif) ligand 16; Acts as a scavenger receptor on macrophages, which specifica [...] (273 aa)			•	•		0.966
	CCR6	chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC [...] (374 aa)			•	•		0.932
	CCL27	chemokine (C-C motif) ligand 27; Chemotactic factor that attracts skin-associated memory T-lymp [...] (112 aa)			•	•		0.931

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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