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  CHRNE protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CHRNE
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (493 aa)
(Homo sapiens)
Predicted Functional Partners:
NRG1
neuregulin 1; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recrui [...] (645 aa)
       0.939
A1BG
alpha-1-B glycoprotein (495 aa)
       0.938
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
      0.899
HRG
histidine-rich glycoprotein; The physiological function is not yet known. It binds heme, dyes a [...] (525 aa)
       0.870
RAPSN
receptor-associated protein of the synapse; Thought to play some role in anchoring or stabilizi [...] (412 aa)
       0.865
UTRN
utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) (3433 aa)
       0.860
DOK7
docking protein 7; Probable muscle-intrinsic activator of MUSK that plays an essential role in [...] (504 aa)
       0.812
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; An [...] (455 aa)
       0.808
ACHE
acetylcholinesterase (Yt blood group); Terminates signal transduction at the neuromuscular junc [...] (617 aa)
       0.784
AGRN
agrin; Component of the basal lamina that causes the aggregation of acetylcholine receptors and [...] (2045 aa)
       0.781
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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