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  DOCK8 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DOCK8
dedicator of cytokinesis 8; Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP (By similarity) (2031 aa)
(Homo sapiens)
Predicted Functional Partners:
KANK1
KN motif and ankyrin repeat domains 1; Potential tumor suppressor for renal cell carcinoma (1352 aa)
       0.908
DMRT1
doublesex and mab-3 related transcription factor 1; May be required for testis development (373 aa)
       0.887
TYK2
tyrosine kinase 2; Probably involved in intracellular signal transduction by being involved in [...] (1187 aa)
       0.821
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
      0.784
RHOJ
ras homolog gene family, member J; GTP-binding protein with GTPase activity. Elicits the format [...] (214 aa)
      0.709
PNLIPRP3
pancreatic lipase-related protein 3 (467 aa)
       0.708
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor); Transcription [...] (770 aa)
       0.704
RHOQ
ras homolog gene family, member Q; Plasma membrane-associated small GTPase which cycles between [...] (205 aa)
      0.683
LDOC1
leucine zipper, down-regulated in cancer 1; May have an important role in the development and/o [...] (146 aa)
       0.667
CDH15
cadherin 15, type 1, M-cadherin (myotubule); Cadherins are calcium dependent cell adhesion prot [...] (814 aa)
       0.653
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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