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  GDF6 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GDF6
growth differentiation factor 6; Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Play a key role in establishing boundaries between skeletal elements during development (By similarity) (455 aa)
(Homo sapiens)
Predicted Functional Partners:
NOG
noggin; Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogene [...] (232 aa)
      0.975
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase); On ligand binding, form [...] (1038 aa)
     0.968
ACAN
aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissu [...] (2416 aa)
       0.946
HES7
hairy and enhancer of split 7 (Drosophila); Transcriptional repressor. Represses transcription [...] (225 aa)
       0.902
SMAD5
SMAD family member 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) [...] (464 aa)
      0.851
AMHR2
anti-Mullerian hormone receptor, type II; On ligand binding, forms a receptor complex consistin [...] (573 aa)
      0.800
CHRD
chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryon [...] (955 aa)
       0.800
BMPR1B
bone morphogenetic protein receptor, type IB; On ligand binding, forms a receptor complex consi [...] (502 aa)
      0.780
AFMID
arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second [...] (308 aa)
       0.778
PAEP
progestagen-associated endometrial protein; This protein is, quantitatively, the main protein s [...] (180 aa)
       0.777
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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