version_number_image
  FLCN protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FLCN
folliculin; May play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (579 aa)
(Homo sapiens)
Predicted Functional Partners:
FNIP1
folliculin interacting protein 1; May be involved in energy and/or nutrient sensing through the [...] (1166 aa)
      0.996
FNIP2
folliculin interacting protein 2; May be involved in energy and/or nutrient sensing through the [...] (1114 aa)
       0.984
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit; Responsible for the regulation of fat [...] (552 aa)
      0.949
MTOR
mechanistic target of rapamycin (serine/threonine kinase); Kinase subunit of both mTORC1 and mT [...] (2549 aa)
       0.945
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit; AMPK is responsible for the regul [...] (331 aa)
       0.843
PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit; Responsible for the regulation of fat [...] (574 aa)
       0.825
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit; AMPK is responsible for the regula [...] (270 aa)
       0.794
PRCC
papillary renal cell carcinoma (translocation-associated) (491 aa)
       0.776
TSC2
tuberous sclerosis 2; In complex with TSC1, inhibits the nutrient-mediated or growth factor-sti [...] (1807 aa)
       0.763
FH
fumarate hydratase; Also acts as a tumor suppressor (510 aa)
       0.760
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (6%)
Permalink