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  DLAT protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DLAT
dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (647 aa)
(Homo sapiens)
Predicted Functional Partners:
PDHB
pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overa [...] (359 aa)
 0.999
DLD
dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage [...] (509 aa)
 0.998
PDK3
pyruvate dehydrogenase kinase, isozyme 3; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (415 aa)
     0.998
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the ov [...] (390 aa)
  0.998
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2; The pyruvate dehydrogenase complex catalyzes the ov [...] (388 aa)
  0.993
PDK2
pyruvate dehydrogenase kinase, isozyme 2; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (407 aa)
     0.992
PDHX
pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogen [...] (501 aa)
  0.982
PDK4
pyruvate dehydrogenase kinase, isozyme 4; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (411 aa)
     0.961
CS
citrate synthase (466 aa)
     0.953
ACLY
ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cyt [...] (1101 aa)
      0.920
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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