version_number_image
  PITX1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PITX1
paired-like homeodomain 1; May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb (314 aa)
(Homo sapiens)
Predicted Functional Partners:
TBX4
T-box 4; Involved in the transcriptional regulation of genes required for mesoderm differentiat [...] (545 aa)
       0.989
TBX19
T-box 19; Transcriptional regulator involved in developmental processes. Can activate POMC gene [...] (448 aa)
       0.971
LHB
luteinizing hormone beta polypeptide; Promotes spermatogenesis and ovulation by stimulating the [...] (141 aa)
       0.958
TBX5
T-box 5; Involved in the transcriptional regulation of genes required for mesoderm differentiat [...] (518 aa)
       0.921
POU1F1
POU class 1 homeobox 1; Transcription factor involved in the specification of the lactotrope, s [...] (317 aa)
      0.918
EGR1
early growth response 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5' [...] (543 aa)
      0.917
SHROOM3
shroom family member 3; Controls cell shape changes in the neuroepithelium during neural tube c [...] (1996 aa)
       0.882
NR5A1
nuclear receptor subfamily 5, group A, member 1; Transcriptional activator. Seems to be essenti [...] (461 aa)
      0.861
SMAD3
SMAD family member 3; Transcriptional modulator activated by TGF-beta (transforming growth fact [...] (425 aa)
       0.846
TERT
telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the re [...] (1132 aa)
       0.815
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (3%)
Permalink