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  TRPV5 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TRPV5
transient receptor potential cation channel, subfamily V, member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)- dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity) (729 aa)
(Homo sapiens)
Predicted Functional Partners:
SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; Scaffold protein tha [...] (337 aa)
      0.948
KL
klotho; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks e [...] (1012 aa)
       0.918
CALB1
calbindin 1, 28kDa; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3', [...] (261 aa)
      0.913
S100A10
S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may [...] (97 aa)
      0.888
GUSB
glucuronidase, beta; Plays an important role in the degradation of dermatan and keratan sulfate [...] (651 aa)
       0.861
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)
       0.861
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1; This magnesium-dependent enzyme catalyzes the hyd [...] (1220 aa)
       0.850
NIPSNAP1
nipsnap homolog 1 (C. elegans) (284 aa)
       0.799
CAT
catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from [...] (527 aa)
       0.786
SLC7A3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; Mediates the up [...] (619 aa)
       0.784
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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