TRPV5 protein (Homo sapiens) - STRING interaction network

TRPV5 protein (Homo sapiens) - STRING interaction network

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	TRPV5	transient receptor potential cation channel, subfamily V, member 5; Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)- dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity) (729 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; Scaffold protein tha [...] (337 aa)	•	•	0.948
	KL	klotho; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks e [...] (1012 aa)		•	0.918
	CALB1	calbindin 1, 28kDa; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3', [...] (261 aa)	•	•	0.913
	S100A10	S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may [...] (97 aa)	•	•	0.888
	GUSB	glucuronidase, beta; Plays an important role in the degradation of dermatan and keratan sulfate [...] (651 aa)		•	0.861
	PTH	parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)		•	0.861
	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1; This magnesium-dependent enzyme catalyzes the hyd [...] (1220 aa)		•	0.850
	NIPSNAP1	nipsnap homolog 1 (C. elegans) (284 aa)		•	0.799
	CAT	catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from [...] (527 aa)		•	0.786
	SLC7A3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; Mediates the up [...] (619 aa)		•	0.784

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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