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  TNFRSF8 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TNFRSF8
tumor necrosis factor receptor superfamily, member 8; Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B (595 aa)
(Homo sapiens)
Predicted Functional Partners:
TRAF2
TNF receptor-associated factor 2; Adapter protein and signal transducer that links members of t [...] (501 aa)
      0.999
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8; Cytokine that binds to TNFRSF8/CD30. Indu [...] (234 aa)
     0.999
TRAF5
TNF receptor-associated factor 5; Adapter protein and signal transducer that links members of t [...] (557 aa)
      0.998
TRAF1
TNF receptor-associated factor 1; Adapter protein and signal transducer that links members of t [...] (416 aa)
      0.991
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.989
TRAF3
TNF receptor-associated factor 3; Adapter protein and signal transducer that links members of t [...] (568 aa)
      0.971
CD28
CD28 molecule; Involved in T-cell activation, the induction of cell proliferation and cytokine [...] (220 aa)
       0.961
IL2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
       0.960
ICAM1
intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein [...] (532 aa)
       0.956
IL4
interleukin 4; Participates in at least several B-cell activation processes as well as of other [...] (153 aa)
       0.954
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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