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  XRCC1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1; Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents (633 aa)
(Homo sapiens)
Predicted Functional Partners:
LIG3
ligase III, DNA, ATP-dependent; Interacts with DNA-repair protein XRCC1 and can correct defecti [...] (1009 aa)
     0.999
POLB
polymerase (DNA directed), beta; Repair polymerase. Conducts "gap-filling" DNA synthesis in a s [...] (335 aa)
     0.999
APTX
aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA br [...] (342 aa)
      0.999
PARP1
poly (ADP-ribose) polymerase 1; Involved in the base excision repair (BER) pathway, by catalyzi [...] (1014 aa)
      0.986
NOL9
nucleolar protein 9 (702 aa)
       0.986
APLF
aprataxin and PNKP like factor; Nuclease involved in single-strand and double-strand DNA break [...] (511 aa)
      0.985
OGG1
8-oxoguanine DNA glycosylase; DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7, [...] (424 aa)
      0.986
E2F1
E2F transcription factor 1; Transcription activator that binds DNA cooperatively with dp protei [...] (437 aa)
      0.983
PNKP
polynucleotide kinase 3'-phosphatase; Catalyzes the phosphorylation of DNA at 5'-hydroxyl termi [...] (521 aa)
      0.981
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase; Poly [ADP-ribose] polymerase using NAD(+) as a subs [...] (657 aa)
      0.977
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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