SRCAP protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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Snf2-related CREBBP activator protein; Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription (3230 aa)
(Homo sapiens)
Predicted Functional Partners:
H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset o [...] (128 aa)
vacuolar protein sorting 72 homolog (S. cerevisiae); Could be a DNA-binding transcriptional reg [...] (364 aa)
RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (463 aa)
zinc finger, HIT type 1; Seems to play a role in p53-mediated apoptosis induction (154 aa)
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
GTPase activating protein (SH3 domain) binding protein 1; May be a regulated effector of stress [...] (466 aa)
histone cluster 2, H2ac; Variant histone H2A which replaces conventional H2A in a subset of nuc [...] (129 aa)
YEATS domain containing 4; Component of the NuA4 histone acetyltransferase (HAT) complex which [...] (227 aa)
motor neuron and pancreas homeobox 1; Putative transcription factor involved in pancreas develo [...] (401 aa)
coactivator-associated arginine methyltransferase 1; Methylates (mono- and asymmetric dimethyla [...] (608 aa)
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Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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