CALCOCO1 protein (Homo sapiens) - STRING interaction network

CALCOCO1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CALCOCO1	calcium binding and coiled-coil domain 1; Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1- mediated transcriptional activation via its inte [...] (691 aa)
		(Homo sapiens)
Predicted Functional Partners:
	IPP	intracisternal A particle-promoted polypeptide; May play a role in organizing the actin cytoske [...] (584 aa)	•	•	0.926
	EP300	microRNA 1281; Functions as histone acetyltransferase and regulates transcription via chromatin [...] (2414 aa)	•	•	0.882
	CALCB	calcitonin-related polypeptide beta; CGRP induces vasodilation. It dilates a variety of vessels [...] (127 aa)		•	0.800
	CARM1	coactivator-associated arginine methyltransferase 1; Methylates (mono- and asymmetric dimethyla [...] (608 aa)		•	0.694
	TNFRSF25	tumor necrosis factor receptor superfamily, member 25; Receptor for TNFSF12/APO3L/TWEAK. Intera [...] (426 aa)		•	0.692
	HPS1	Hermansky-Pudlak syndrome 1; Component of multiple cytoplasmic organelles. Apparently crucial f [...] (700 aa)		•	0.649
	CRYBA2	crystallin, beta A2; Crystallins are the dominant structural components of the vertebrate eye l [...] (197 aa)	•		0.643
	CREBBP	CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)	•	•	0.623
	CTNNBL1	catenin, beta like 1; Induces apoptosis in CHO cells (563 aa)	•		0.619
	HIST1H4A	histone cluster 1, H4a; Core component of nucleosome. Nucleosomes wrap and compact DNA into chr [...] (103 aa)	•		0.619

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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