version_number_image
  CALCOCO1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CALCOCO1
calcium binding and coiled-coil domain 1; Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1- mediated transcriptional activation via its inte [...] (691 aa)
(Homo sapiens)
Predicted Functional Partners:
IPP
intracisternal A particle-promoted polypeptide; May play a role in organizing the actin cytoske [...] (584 aa)
      0.926
EP300
microRNA 1281; Functions as histone acetyltransferase and regulates transcription via chromatin [...] (2414 aa)
      0.882
CALCB
calcitonin-related polypeptide beta; CGRP induces vasodilation. It dilates a variety of vessels [...] (127 aa)
       0.800
CARM1
coactivator-associated arginine methyltransferase 1; Methylates (mono- and asymmetric dimethyla [...] (608 aa)
       0.694
TNFRSF25
tumor necrosis factor receptor superfamily, member 25; Receptor for TNFSF12/APO3L/TWEAK. Intera [...] (426 aa)
       0.692
HPS1
Hermansky-Pudlak syndrome 1; Component of multiple cytoplasmic organelles. Apparently crucial f [...] (700 aa)
       0.649
CRYBA2
crystallin, beta A2; Crystallins are the dominant structural components of the vertebrate eye l [...] (197 aa)
       0.643
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
      0.623
CTNNBL1
catenin, beta like 1; Induces apoptosis in CHO cells (563 aa)
       0.619
HIST1H4A
histone cluster 1, H4a; Core component of nucleosome. Nucleosomes wrap and compact DNA into chr [...] (103 aa)
       0.619
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (11%)
Permalink