TRPV4 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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transient receptor potential cation channel, subfamily V, member 4; Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism (871 aa)
(Homo sapiens)
Predicted Functional Partners:
microtubule-associated protein 7; Microtubule-stabilizing protein that may play an important ro [...] (749 aa)
aquaporin 4; Forms a water-specific channel. Osmoreceptor which regulates body water balance an [...] (323 aa)
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)
catenin (cadherin-associated protein), beta 1, 88kDa; Involved in the regulation of cell adhesi [...] (781 aa)
progesterone receptor; The steroid hormones and their receptors are involved in the regulation [...] (933 aa)
cytochrome P450, family 2, subfamily J, polypeptide 2; This enzyme metabolizes arachidonic acid [...] (502 aa)
ubiquitin protein ligase E3B; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ub [...] (1068 aa)
kinesin family member 1B; Motor for anterograde transport of mitochondria. Has a microtubule pl [...] (1770 aa)
transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor- [...] (759 aa)
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