version_number_image
  CYBA protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CYBA
cytochrome b-245, alpha polypeptide; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide (195 aa)
(Homo sapiens)
Predicted Functional Partners:
NCF2
neutrophil cytosolic factor 2; NCF2, NCF1, and a membrane bound cytochrome b558 are required fo [...] (526 aa)
    0.999
CYBB
cytochrome b-245, beta polypeptide; Critical component of the membrane-bound oxidase of phagocy [...] (570 aa)
     0.999
NCF1C
neutrophil cytosolic factor 1C pseudogene; NCF2, NCF1, and a membrane bound cytochrome b558 are [...] (390 aa)
     0.999
NCF1
neutrophil cytosolic factor 1; May be required for activation of the latent NADPH oxidase (nece [...] (390 aa)
     0.999
NOX1
NADPH oxidase 1; NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of re [...] (564 aa)
     0.999
NCF4
neutrophil cytosolic factor 4, 40kDa; Component of the NADPH-oxidase, a multicomponent enzyme s [...] (348 aa)
    0.999
NOXO1
NADPH oxidase organizer 1; Constitutively potentiates the superoxide-generating activity of NOX [...] (376 aa)
      0.997
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
     0.994
NOX3
NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a com [...] (568 aa)
      0.994
NOXA1
NADPH oxidase activator 1; Functions as an activator of NOX1, a superoxide- producing NADPH oxi [...] (483 aa)
      0.988
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (5%)
Permalink