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  CCL21 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CCL21
chemokine (C-C motif) ligand 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs (134 aa)
(Homo sapiens)
Predicted Functional Partners:
CCR7
chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of E [...] (378 aa)
     0.999
CXCL13
chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, mon [...] (109 aa)
     0.998
CXCR5
chemokine (C-X-C motif) receptor 5; Cytokine receptor that binds to B-lymphocyte chemoattractan [...] (372 aa)
     0.998
CXCR3
chemokine (C-X-C motif) receptor 3; Receptor for CXCL9, CXCL10 and CXCL11 and mediates the prol [...] (415 aa)
      0.996
CCL27
chemokine (C-C motif) ligand 27; Chemotactic factor that attracts skin-associated memory T-lymp [...] (112 aa)
      0.995
CXCR4
chemokine (C-X-C motif) receptor 4; Receptor for the C-X-C chemokine CXCL12/SDF-1. Transduces a [...] (356 aa)
      0.991
CXCL10
chemokine (C-X-C motif) ligand 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (98 aa)
      0.990
CCR5
chemokine (C-C motif) receptor 5; Receptor for a number of inflammatory CC-chemokines including [...] (352 aa)
      0.987
CCR6
chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC [...] (374 aa)
      0.985
CXCL9
chemokine (C-X-C motif) ligand 9; Cytokine that affects the growth, movement, or activation sta [...] (125 aa)
      0.981
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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