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  MYST2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MYST2
MYST histone acetyltransferase 2; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription (611 aa)
(Homo sapiens)
Predicted Functional Partners:
ING4
inhibitor of growth family, member 4; Component of the HBO1 complex which has a histone H4- spe [...] (249 aa)
     0.999
PHF17
PHD finger protein 17; Component of the HBO1 complex which has a histone H4- specific acetyltra [...] (842 aa)
     0.997
PHF15
PHD finger protein 15; Component of the HBO1 complex which has a histone H4- specific acetyltra [...] (790 aa)
     0.985
PHF16
PHD finger protein 16; Component of the HBO1 complex which has a histone H4- specific acetyltra [...] (823 aa)
     0.985
ING5
inhibitor of growth family, member 5; Component of the HBO1 complex which has a histone H4- spe [...] (240 aa)
      0.983
AR
androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that re [...] (920 aa)
      0.946
PLK1
polo-like kinase 1 (Drosophila); Serine/threonine-protein kinase that performs several importan [...] (603 aa)
      0.946
MCM2
minichromosome maintenance complex component 2; Acts as a factor that allows the DNA to undergo [...] (904 aa)
      0.917
CDT1
chromatin licensing and DNA replication factor 1; Cooperates with CDC6 to promote the loading o [...] (546 aa)
      0.882
MEAF6
MYST/Esa1-associated factor 6; Component of the NuA4 histone acetyltransferase complex which is [...] (201 aa)
      0.873
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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