version_number_image
  PDGFRA protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide; Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity (1089 aa)
(Homo sapiens)
Predicted Functional Partners:
PDGFA
platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor is a potent mi [...] (211 aa)
     0.998
PDGFC
platelet derived growth factor C; Potent mitogen and chemoattractant for cells of mesenchymal o [...] (345 aa)
     0.997
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) [...] (241 aa)
     0.995
SHF
Src homology 2 domain containing F; Adapter protein which may play a role in the regulation of [...] (423 aa)
     0.994
PDGFRB
platelet-derived growth factor receptor, beta polypeptide; Receptor that binds specifically to [...] (1106 aa)
    0.993
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha); Binds to activated (phosphorylated) pr [...] (724 aa)
     0.991
CRK
v-crk sarcoma virus CT10 oncogene homolog (avian); The Crk-I and Crk-II forms differ in their b [...] (304 aa)
     0.988
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.981
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
     0.980
SHB
Src homology 2 domain containing adaptor protein B; Adapter protein which regulates several sig [...] (509 aa)
     0.975
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (3%)
Permalink