FUS protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity (526 aa)
(Homo sapiens)
Predicted Functional Partners:
splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for 'A' comp [...] (464 aa)
splicing factor, arginine/serine-rich 2; Necessary for the splicing of pre-mRNA. It is required [...] (221 aa)
Y box binding protein 1; Binds to splice sites in pre-mRNA and regulates splice site selection. [...] (324 aa)
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; DNA-dependent RNA polymerase catalyze [...] (1970 aa)
protein arginine methyltransferase 1; Methylates (mono and asymmetric dimethylation) the guanid [...] (371 aa)
splicing factor, arginine/serine-rich 4; A probable role in alternative splice site selection d [...] (494 aa)
polypyrimidine tract binding protein 1; Plays a role in pre-mRNA splicing. Binds to the polypyr [...] (557 aa)
serine/arginine repetitive matrix 1; Part of pre- and post-splicing multiprotein mRNP complexes [...] (904 aa)
proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)
REV1 homolog (S. cerevisiae); Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP [...] (1251 aa)
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network


Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (11%)