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  IDO1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IDO1
indoleamine 2,3-dioxygenase 1; Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen (403 aa)
(Homo sapiens)
Predicted Functional Partners:
KYNU
kynureninase (L-kynurenine hydrolase); Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- [...] (465 aa)
     0.985
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
       0.985
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.981
WARS
tryptophanyl-tRNA synthetase; Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity wh [...] (471 aa)
     0.978
IRF1
interferon regulatory factor 1; Specifically binds to the upstream regulatory region of type I [...] (325 aa)
      0.961
TDO2
tryptophan 2,3-dioxygenase; Incorporates oxygen into the indole moiety of tryptophan. Has a bro [...] (406 aa)
      0.958
IL2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
       0.951
PDC
phosducin; May participate in the regulation of visual phototransduction or in the integration [...] (246 aa)
       0.933
TPH1
tryptophan hydroxylase 1 (444 aa)
      0.920
TNFRSF18
tumor necrosis factor receptor superfamily, member 18; Receptor for TNFSF18. Seems to be involv [...] (255 aa)
       0.919
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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