version_number_image
  MAS1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MAS1
MAS1 oncogene; Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1 (325 aa)
(Homo sapiens)
Predicted Functional Partners:
REN
renin; Renin is a highly specific endopeptidase, whose only known function is to generate angio [...] (406 aa)
       0.960
NPFF
neuropeptide FF-amide peptide precursor; Morphine modulating peptides. Have wide-ranging physio [...] (113 aa)
       0.895
IGF2R
insulin-like growth factor 2 receptor; Transport of phosphorylated lysosomal enzymes from the G [...] (2491 aa)
       0.826
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Essential component of the ren [...] (485 aa)
      0.812
CGB2
chorionic gonadotropin, beta polypeptide 2 (163 aa)
       0.786
CGB
chorionic gonadotropin, beta polypeptide; Stimulates the ovaries to synthesize the steroids tha [...] (165 aa)
       0.786
CGB7
chorionic gonadotropin, beta polypeptide 7 (165 aa)
       0.786
CGB8
chorionic gonadotropin, beta polypeptide 8 (165 aa)
       0.786
CGB5
chorionic gonadotropin, beta polypeptide 5 (165 aa)
       0.786
CGB1
chorionic gonadotropin, beta polypeptide 1 (155 aa)
       0.786
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (7%)
Permalink