SNRPA protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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small nuclear ribonucleoprotein polypeptide A; Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process (282 aa)
(Homo sapiens)
Predicted Functional Partners:
splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for 'A' comp [...] (464 aa)
small nuclear ribonucleoprotein 70kDa (U1); Mediates the splicing of pre-mRNA by binding to the [...] (437 aa)
small nuclear ribonucleoprotein polypeptide C; This protein is associated with snRNP U1 (159 aa)
U2 small nuclear RNA auxiliary factor 2; Necessary for the splicing of pre-mRNA. Binds to the p [...] (475 aa)
U6 snRNA-associated Sm-like protein LSm2 (snRNP core Sm-like protein Sm-x5)(Small nuclear ribon [...] (95 aa)
polypyrimidine tract binding protein 1; Plays a role in pre-mRNA splicing. Binds to the polypyr [...] (557 aa)
splicing factor, arginine/serine-rich 1; Plays a role in preventing exon skipping, ensuring the [...] (248 aa)
small nuclear ribonucleoprotein polypeptide F; Appears to function in the U7 snRNP complex that [...] (86 aa)
small nuclear ribonucleoprotein polypeptide G; Appears to function in the U7 snRNP complex that [...] (76 aa)
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23; Probably involved in pre-mRNA splicing (820 aa)
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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