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  GSC protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GSC
goosecoid homeobox; Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis (257 aa)
(Homo sapiens)
Predicted Functional Partners:
SMAD2
SMAD family member 2; Transcriptional modulator activated by TGF-beta and activin type 1 recept [...] (467 aa)
     0.972
FOXH1
forkhead box H1; Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT] [...] (365 aa)
     0.971
SMAD4
SMAD family member 4; Common mediator of signal transduction by TGF-beta (transforming growth f [...] (552 aa)
     0.950
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1; Binds to the PU-box, a pu [...] (271 aa)
      0.943
LDB1
LIM domain binding 1; Binds to the LIM domain of a wide variety of LIM domain- containing trans [...] (411 aa)
       0.920
TFDP1
transcription factor Dp-1; Can stimulate E2F-dependent transcription. Binds DNA cooperatively w [...] (410 aa)
       0.899
E2F2
E2F transcription factor 2; Transcription activator that binds DNA cooperatively with DP protei [...] (437 aa)
       0.899
E2F1
E2F transcription factor 1; Transcription activator that binds DNA cooperatively with dp protei [...] (437 aa)
       0.899
RB1
retinoblastoma 1; Key regulator of entry into cell division that acts as a tumor suppressor. Ac [...] (928 aa)
       0.899
E2F3
E2F transcription factor 3; Transcription activator that binds DNA cooperatively with DP protei [...] (465 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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