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  PKD2 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PKD2
polycystic kidney disease 2 (autosomal dominant); Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis (968 aa)
(Homo sapiens)
Predicted Functional Partners:
TRPC1
transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor- [...] (759 aa)
      0.985
PKD1
polycystic kidney disease 1 (autosomal dominant); May be an ion-channel regulator. PKD1 and PKD [...] (4303 aa)
     0.984
HAX1
HCLS1 associated protein X-1; Promotes cell survival. Potentiates GNA13-mediated cell migration [...] (279 aa)
      0.962
KIF3A
kinesin family member 3A; Microtubule-based anterograde translocator for membranous organelles. [...] (699 aa)
       0.960
PRKD1
protein kinase D1; Converts transient diacylglycerol (DAG) signals into prolonged physiological [...] (912 aa)
       0.950
CD2AP
CD2-associated protein; Seems to act as an adapter protein between membrane proteins and the ac [...] (639 aa)
      0.930
KRT17
keratin 17; May play a role in the formation and maintenance of various skin appendages, specif [...] (432 aa)
       0.930
PRKCSH
protein kinase C substrate 80K-H; Regulatory subunit of glucosidase II (528 aa)
       0.923
PCSK2
proprotein convertase subtilisin/kexin type 2; Involved in the processing of hormone and other [...] (638 aa)
       0.895
SCG5
secretogranin V (7B2 protein); Acts as a molecular chaperone for PCSK2/PC2, preventing its prem [...] (212 aa)
       0.894
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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