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  APOA1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
APOA1
apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (267 aa)
(Homo sapiens)
Predicted Functional Partners:
LCAT
lecithin-cholesterol acyltransferase; Central enzyme in the extracellular metabolism of plasma [...] (440 aa)
     0.999
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1; cAMP-dependent and sulfonylurea-sensitive [...] (2261 aa)
     0.999
APOA2
apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association [...] (100 aa)
     0.999
APOC3
apolipoprotein C-III; Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake o [...] (99 aa)
    0.999
APOB
apolipoprotein B (including Ag(x) antigen); Apolipoprotein B is a major protein constituent of [...] (4563 aa)
    0.997
CETP
cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl e [...] (493 aa)
     0.996
HNF4A
hepatocyte nuclear factor 4, alpha; Transcriptionally controlled transcription factor. Binds to [...] (474 aa)
      0.994
PLTP
phospholipid transfer protein; Converts HDL into larger and smaller particles. May play a key r [...] (493 aa)
      0.994
SCARB1
scavenger receptor class B, member 1; Receptor for different ligands such as phospholipids, cho [...] (509 aa)
      0.984
LPL
lipoprotein lipase; The primary function of this lipase is the hydrolysis of triglycerides of c [...] (475 aa)
      0.983
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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