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  PRTN3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PRTN3
proteinase 3; Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters (256 aa)
(Homo sapiens)
Predicted Functional Partners:
IL32
interleukin 32; Cytokine that may play a role in innate and adaptive immune responses. It induc [...] (188 aa)
      0.990
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1; Binds to the PU-box, a pu [...] (271 aa)
      0.988
MYB
v-myb myeloblastosis viral oncogene homolog (avian); Transcriptional activator; DNA-binding pro [...] (761 aa)
      0.984
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1; Regulates the activity of the neutro [...] (379 aa)
      0.963
PI3
peptidase inhibitor 3, skin-derived; Neutrophil and pancreatic elastase-specific inhibitor of s [...] (117 aa)
       0.952
CD177
CD177 molecule (248 aa)
       0.950
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.947
PROCR
protein C receptor, endothelial (EPCR); Binds activated protein C. Enhances protein C activatio [...] (238 aa)
       0.902
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta; C/EBP is a DNA-binding protein that recognizes t [...] (269 aa)
      0.899
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta; Important transcriptional activator in the regula [...] (345 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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