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  SCNN1A protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SCNN1A
sodium channel, nonvoltage-gated 1 alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (669 aa)
(Homo sapiens)
Predicted Functional Partners:
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like; E3 ubiquitin-protein li [...] (975 aa)
     0.999
NEDD4
neural precursor cell expressed, developmentally down-regulated 4; E3 ubiquitin-protein ligase [...] (1247 aa)
      0.999
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucoco [...] (778 aa)
       0.965
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member [...] (1480 aa)
       0.965
SGK1
serum/glucocorticoid regulated kinase 1; Protein kinase that plays an important role in cellula [...] (526 aa)
       0.898
STX1A
syntaxin 1A (brain); Potentially involved in docking of synaptic vesicles at presynaptic active [...] (288 aa)
      0.892
UBC
ubiquitin C (685 aa)
       0.889
REN
renin; Renin is a highly specific endopeptidase, whose only known function is to generate angio [...] (406 aa)
       0.873
NR3C2
nuclear receptor subfamily 3, group C, member 2; Receptor for both mineralocorticoids (MC) such [...] (984 aa)
       0.853
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11; Participates in physiological process [...] (1382 aa)
       0.846
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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