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  WFS1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
WFS1
Wolfram syndrome 1 (wolframin); Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (890 aa)
(Homo sapiens)
Predicted Functional Partners:
CISD2
CDGSH iron sulfur domain 2; May play a role in calcium homeostasis (135 aa)
       0.951
SYVN1
synovial apoptosis inhibitor 1, synoviolin; Acts as an E3 ubiquitin-protein ligase which accept [...] (617 aa)
      0.930
SHC1
SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)
       0.899
CXXC1
CXXC finger 1 (PHD domain); Transcriptional activator that exhibits a unique DNA binding specif [...] (660 aa)
       0.899
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; Required for the ret [...] (220 aa)
       0.899
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2; Preferenti [...] (271 aa)
       0.899
YIF1A
Yip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasm [...] (293 aa)
       0.899
ZBTB17
zinc finger and BTB domain containing 17; May function as a housekeeping DNA-binding protein th [...] (803 aa)
       0.899
TSPYL2
TSPY-like 2; Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expressi [...] (693 aa)
       0.899
LMNA
lamin A/C; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic si [...] (664 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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