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  ESR1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ESR1
estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (595 aa)
(Homo sapiens)
Predicted Functional Partners:
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
     0.999
NCOA1
nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear recept [...] (1441 aa)
      0.999
BRCA1
breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellul [...] (1863 aa)
      0.999
EP300
microRNA 1281; Functions as histone acetyltransferase and regulates transcription via chromatin [...] (2414 aa)
      0.999
NCOA3
nuclear receptor coactivator 3; Nuclear receptor coactivator that directly binds nuclear recept [...] (1424 aa)
      0.999
SP1
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
      0.999
NCOA2
nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear r [...] (1464 aa)
      0.999
IGF1R
insulin-like growth factor 1 receptor; This receptor binds insulin-like growth factor 1 (IGF1) [...] (1367 aa)
     0.999
NRIP1
nuclear receptor interacting protein 1; Modulates transcriptional activation by steroid recepto [...] (1158 aa)
     0.999
PELP1
proline, glutamate and leucine rich protein 1; Coactivator of estrogen receptor-mediated transc [...] (1274 aa)
     0.999
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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