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  GABRA1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel (456 aa)
(Homo sapiens)
Predicted Functional Partners:
CLCN2
chloride channel 2; Voltage-gated chloride channel. Chloride channels have several functions in [...] (898 aa)
       0.870
EFHC1
EF-hand domain (C-terminal) containing 1; May enhance calcium influx through CACNA1E and stimul [...] (640 aa)
       0.867
CREB1
cAMP responsive element binding protein 1; This protein binds the cAMP response element (CRE), [...] (341 aa)
       0.851
DRD4
dopamine receptor D4 (419 aa)
      0.849
SCN1B
sodium channel, voltage-gated, type I, beta; Crucial in the assembly, expression, and functiona [...] (268 aa)
       0.815
SCN1A
sodium channel, voltage-gated, type I, alpha subunit; Mediates the voltage-dependent sodium ion [...] (1998 aa)
       0.802
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3; Probably important in the regula [...] (872 aa)
       0.754
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2; Probably important in the regula [...] (872 aa)
       0.748
GAD1
glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)
       0.747
CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit; Voltage-sensitive calcium channel [...] (2353 aa)
       0.731
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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