CRY1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.

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cryptochrome 1 (photolyase-like); Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL (By similarity) (586 aa)
(Homo sapiens)
Predicted Functional Partners:
period homolog 2 (Drosophila); Component of the circadian clock mechanism which is essential fo [...] (1255 aa)
aryl hydrocarbon receptor nuclear translocator-like; ARNTL-CLOCK heterodimers activate E-box el [...] (625 aa)
period homolog 1 (Drosophila); Component of the circadian clock mechanism which is essential fo [...] (1290 aa)
clock homolog (mouse); ARNTL/2-CLOCK heterodimers activate E-box element (3'- CACGTG-5') transc [...] (846 aa)
period homolog 3 (Drosophila); Component of the circadian clock mechanism which is essential fo [...] (1201 aa)
neuronal PAS domain protein 2; BMAL1-NPAS2 heterodimers activate E-box element (3'- CACGTG-5') [...] (824 aa)
casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utiliz [...] (416 aa)
basic helix-loop-helix family, member e41; May be a transcriptional repressor that represses bo [...] (482 aa)
RAR-related orphan receptor A; Orphan nuclear receptor. Binds DNA as a monomer to hormone respo [...] (556 aa)
nuclear receptor subfamily 1, group D, member 1; Functions as a constitutive transcriptional re [...] (614 aa)
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Co-expression Experiments Databases Textmining
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