TRIO protein (Homo sapiens) - STRING interaction network

TRIO protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	TRIO	triple functional domain (PTPRF interacting); Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth (3097 aa)
		(Homo sapiens)
Predicted Functional Partners:
	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)	•	•	•	0.998
	RHOA	ras homolog gene family, member A; Regulates a signal transduction pathway linking plasma membr [...] (193 aa)	•		•	0.988
	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Plasma [...] (192 aa)	•		•	0.925
	RHOG	ras homolog gene family, member G (rho G); Required for the formation of membrane ruffles durin [...] (191 aa)			•	0.925
	PLEK	pleckstrin; Major protein kinase C substrate of platelets, its exact function is not known (350 aa)			•	0.914
	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium dependent cell adhesion pr [...] (796 aa)			•	0.878
	NTN1	netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its ass [...] (604 aa)			•	0.861
	PTPN3	protein tyrosine phosphatase, non-receptor type 3; May act at junctions between the membrane an [...] (913 aa)			•	0.854
	DNTT	deoxynucleotidyltransferase, terminal; Template-independent DNA polymerase which catalyzes the [...] (509 aa)			•	0.824
	CDC42	cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)			•	0.786

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: low (8%)

Permalink