EZR protein (Homo sapiens) - STRING interaction network

EZR protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	EZR	ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (586 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; Scaffold protein tha [...] (358 aa)	•		•	0.999
	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; Scaffold protein tha [...] (337 aa)	•		•	0.998
	PALLD	palladin, cytoskeletal associated protein; Cytoskeletal protein required for organization of no [...] (1106 aa)	•	•	•	0.996
	SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1; Involved in pH regulation to eli [...] (815 aa)		•	•	0.994
	ICAM1	intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein [...] (532 aa)	•	•	•	0.993
	CD44	CD44 molecule (Indian blood group); Receptor for hyaluronic acid (HA). Mediates cell-cell and c [...] (742 aa)	•		•	0.993
	SDC2	syndecan 2; Cell surface proteoglycan that bears heparan sulfate (201 aa)	•	•	•	0.992
	ETV5	ets variant 5; Binds to DNA sequences containing the consensus nucleotide core sequence GGAA (510 aa)			•	0.990
	SPN	sialophorin; One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in th [...] (400 aa)	•		•	0.989
	FASLG	Fas ligand (TNF superfamily, member 6); Cytokine that binds to TNFRSF6/FAS, a receptor that tra [...] (281 aa)	•	•	•	0.981

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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