sd protein (Drosophila melanogaster) - STRING interaction network

sd protein (Drosophila melanogaster) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	sd	scalloped; Transcription factor that functions in the regulation of cell-specific gene expression during development, particularly in the differentiation of the nervous system. When in combination with vestigial (vg) it acts as a transcriptional activation complex that regulates gene expression in the wing. Binding to vg switches the DNA target selectivity of sd. Required autonomously for cell proliferation and viability within the wing blade. Required for proper sensory organ precursor (SOP) differentiation at the wing margin; required for correct expression of sens (440 aa)
		(Drosophila melanogaster)
Predicted Functional Partners:
	vg	vestigial; Involved in determining which thoracic imaginal disk cells will form wings and halte [...] (453 aa)	•	•	0.998
	wg	wingless; Binds as a ligand to a family of frizzled seven- transmembrane receptors and acts thr [...] (468 aa)	•		0.843
	sens	senseless; Transcription factor both necessary and sufficient for proper development of most ce [...] (541 aa)	•		0.843
	ct	cut; Regulator of cell fate decisions in multiple lineages. Specifically, functions as a determ [...] (2383 aa)	•		0.698
	su(Hw)	suppressor of Hairy wing; Component of the gypsy chromatin insulator complex which is required [...] (941 aa)	•		0.698
	pnr	pannier; Transcriptional regulator involved in several developmental processes during embryonic [...] (540 aa)	•		0.653
	yki	yorkie (395 aa)	•	•	0.611
	CG7842	CG7842; Catalyzes the transfer of a malonyl moiety from malonyl- CoA to the free thiol group of [...] (379 aa)		•	0.431
	th	thread; Apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. HtrA2 can antagonize an [...] (438 aa)		•	0.408

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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