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  uvrB protein (Methanobrevibacter smithii) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
uvrB
excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one uvrB monomer. DNA wrap is dependent on ATP binding by uvrB and probably causes local melting of the DNA helix, facilitating insertion of uvrB beta-hairpin between the DNA strands. Then uvrB probes one DNA strand for the presence of a lesion. If a lesion is found the uvrA subunits dissociate [...] (655 aa)
(Methanobrevibacter smithii)
Predicted Functional Partners:
Msm_1581
excinuclease ABC subunit A (963 aa)
   0.999
Msm_1695
excinuclease ABC subunit C (583 aa)
  0.999
prs
ribose-phosphate pyrophosphokinase (298 aa)
       0.942
Msm_1578
hypothetical protein (99 aa)
       0.848
Msm_0001
exoribonuclease VII, large subunit, XseA (527 aa)
       0.758
Msm_1087
NAD-dependent deacetylase (240 aa)
       0.738
Msm_0691
mutator mutT protein (128 aa)
       0.736
Msm_0788
aspartate aminotransferase (370 aa)
       0.724
Msm_1185
methylated-DNA-[protein]-cysteine S-methyltransferase (169 aa)
       0.700
Msm_0895
cation transporter HAD ATPase (818 aa)
       0.674
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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