Vta1 protein (Mus musculus) - STRING interaction network

Vta1 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Vta1	Vps20-associated 1 homolog (S. cerevisiae) Gene; Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies (By similarity). Involved in the sorting and down-regulation of EGFR (309 aa)
		(Mus musculus)
Predicted Functional Partners:
	Vps4a	vacuolar protein sorting 4a (yeast) Gene; Involved in late steps of the endosomal multivesicula [...] (437 aa)		•	•	0.833
	Vps4b	vacuolar protein sorting 4b (yeast) Gene; Involved in late steps of the endosomal multivesicula [...] (444 aa)		•	•	0.828
	Chmp1b	RIKEN cDNA 2610002M06 gene Gene; Probable peripherally associated component of the endosomal so [...] (199 aa)		•		0.800
	Chmp1a	chromatin modifying protein 1A Gene; Probable peripherally associated component of the endosoma [...] (196 aa)		•		0.800
	Chmp5	chromatin modifying protein 5 Gene; Probable peripherally associated component of the endosomal [...] (219 aa)			•	0.775
	Lyst	lysosomal trafficking regulator Gene; May be required for sorting endosomal resident proteins i [...] (3787 aa)	•		•	0.600
	Ngfr	nerve growth factor receptor (TNFR superfamily, member 16) Gene; Low affinity receptor which ca [...] (427 aa)			•	0.537
	Mitd1	MIT, microtubule interacting and transport, domain containing 1 Gene; May play a role in endoso [...] (249 aa)			•	0.409
	Chmp2a	chromatin modifying protein 2A Gene; Probable core component of the endosomal sorting required [...] (222 aa)			•	0.407

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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