Spc24 protein (Mus musculus) - STRING interaction network

Spc24 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	Spc24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) Gene; Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (By similarity) (201 aa)
		(Mus musculus)
Predicted Functional Partners:
	Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae) Gene; Acts as a component of the e [...] (642 aa)		•	•	•	0.999
	Spc25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) Gene; Acts as a component o [...] (226 aa)	•	•	•	•	0.983
	Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) Gene; Acts as a component of [...] (463 aa)			•	•	0.968
	Mis12	MIS12 homolog (yeast) Gene; Part of the MIS12 complex which is required for normal chromosome a [...] (206 aa)		•	•		0.952
	Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) Gene; Involved in cell cycle ch [...] (1059 aa)		•	•		0.950
	Zwint	ZW10 interactor Gene; Part of the MIS12 complex, which is required for kinetochore formation an [...] (252 aa)		•	•		0.945
	Cdca8	cell division cycle associated 8 Gene; Component of the chromosomal passenger complex (CPC), a [...] (326 aa)			•	•	0.929
	Plk1	polo-like kinase 1 (Drosophila) Gene; Serine/threonine-protein kinase that performs several imp [...] (603 aa)			•		0.912
	Cenpa	centromere protein A Gene; Histone H3-like variant which exclusively replaces conventional H3 i [...] (134 aa)			•		0.899
	Cenpo	centromere protein O Gene; Component of the CENPA-CAD (nucleosome distal) complex, a complex re [...] (298 aa)			•		0.899

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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