Unc5b protein (Mus musculus) - STRING interaction network

Unc5b protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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	Unc5b	unc-5 homolog B (C. elegans) Gene; Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity) (945 aa)
		(Mus musculus)
Predicted Functional Partners:
	Dapk1	death associated protein kinase 1 Gene; Calcium/calmodulin-dependent serine/threonine kinase. I [...] (1430 aa)	•	•	•		0.997
	Ntn1	netrin 1 Gene; Netrins control guidance of CNS commissural axons and peripheral motor axons. It [...] (604 aa)	•		•		0.987
	Ntn4	netrin 4 Gene; May play an important role in neural, kidney and vascular development. Promotes [...] (628 aa)	•		•		0.960
	Dcc	deleted in colorectal carcinoma Gene; Receptor for netrin required for axon guidance. Mediates [...] (1447 aa)		•	•	•	0.889
	Alox12	arachidonate 12-lipoxygenase Gene; Oxygenase and 14,15-leukotriene A4 synthase activity (663 aa)			•		0.730
	Dscam	Down syndrome cell adhesion molecule Gene (2013 aa)			•		0.707
	Ntn3	netrin 3 Gene; Netrins control guidance of CNS commissural axons and peripheral motor axons (By [...] (580 aa)			•		0.696
	Ptpn11	protein tyrosine phosphatase, non-receptor type 11 Gene; Acts downstream of various receptor an [...] (597 aa)	•				0.694
	Rpl27a	ribosomal protein L27A Gene (148 aa)			•		0.637
	Rpl7	ribosomal protein L7 Gene; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulat [...] (279 aa)			•		0.637

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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