Rbck1 protein (Mus musculus) - STRING interaction network

Rbck1 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Rbck1	RanBP-type and C3HC4-type zinc finger containing 1 Gene; Might act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination (By similarity) (508 aa)
		(Mus musculus)
Predicted Functional Partners:
	Eya1	eyes absent 1 homolog (Drosophila) Gene; Tyrosine phosphatase that specifically dephosphorylate [...] (591 aa)	•	•		0.849
	Socs6	suppressor of cytokine signaling 6 Gene; SOCS family proteins form part of a classical negative [...] (533 aa)	•	•		0.707
	Uba52	RIKEN cDNA 2810422J05 gene Gene; Protein modifier which can be covalently attached to target ly [...] (232 aa)		•		0.696
	Ube2l3	ubiquitin-conjugating enzyme E2L 3 Gene; Catalyzes the covalent attachment of ubiquitin to othe [...] (154 aa)	•			0.692
	Ireb2	iron responsive element binding protein 2 Gene; RNA-binding protein that binds to iron-responsi [...] (963 aa)		•		0.652
	Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1 Gene; Vacuolar ATPase is responsible for [...] (463 aa)	•	•		0.624
	Rnf31	ring finger protein 31 Gene (1066 aa)	•	•	•	0.621
	Traf2	TNF receptor-associated factor 2 Gene; Adapter protein and signal transducer that links members [...] (508 aa)		•		0.617
	Ube2n	ubiquitin-conjugating enzyme E2N Gene; The UBE2V2/UBE2N heterodimer catalyzes the synthesis of [...] (153 aa)		•		0.577
	Tsg101	tumor susceptibility gene 101 Gene; Component of the ESCRT-I complex, a regulator of vesicular [...] (391 aa)		•		0.543

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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