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  NR0B1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NR0B1
nuclear receptor subfamily 0, group B, member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity) (470 aa)
(Homo sapiens)
Predicted Functional Partners:
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1; Catalyzes the side-chain cleavage react [...] (521 aa)
       0.991
AMH
anti-Mullerian hormone; This glycoprotein, produced by the Sertoli cells of the testis, causes [...] (560 aa)
       0.981
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1; Conversion of pregnenolone and progeste [...] (508 aa)
       0.979
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 [...] (503 aa)
       0.973
WT1
Wilms tumor 1; Transcription factor that plays an important role in cellular development and ce [...] (517 aa)
       0.972
WNT4
wingless-type MMTV integration site family, member 4; Ligand for members of the frizzled family [...] (351 aa)
       0.970
STAR
steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhanc [...] (285 aa)
       0.968
SF1
splicing factor 1; Necessary for the ATP-dependent first step of spliceosome assembly. Binds to [...] (639 aa)
       0.966
NR5A1
nuclear receptor subfamily 5, group A, member 1; Transcriptional activator. Seems to be essenti [...] (461 aa)
     0.964
COPS2
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis); Essential component of the [...] (450 aa)
      0.959
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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