version_number_image
  SERPINI1 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1; Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (410 aa)
(Homo sapiens)
Predicted Functional Partners:
PLAT
plasminogen activator, tissue; Converts the abundant, but inactive, zymogen plasminogen to plas [...] (562 aa)
      0.994
PLG
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
      0.948
MYC
v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene t [...] (454 aa)
      0.907
MAX
MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protei [...] (160 aa)
       0.899
PPIC
peptidylprolyl isomerase C (cyclophilin C); PPIases accelerate the folding of proteins. It cata [...] (212 aa)
       0.873
PLAU
plasminogen activator, urokinase; Specifically cleave the zymogen plasminogen to form the activ [...] (431 aa)
       0.740
SLURP1
secreted LY6/PLAUR domain containing 1; Has an antitumor activity. Was found to be a marker of [...] (103 aa)
       0.684
PLAUR
plasminogen activator, urokinase receptor; Acts as a receptor for urokinase plasminogen activat [...] (335 aa)
       0.678
PDCD10
programmed cell death 10; May play a role in apoptotic pathways (212 aa)
       0.637
RAB33A
RAB33A, member RAS oncogene family (237 aa)
       0.597
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: very high (>100%)
Permalink